Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Angiogenesis"
DOI: 10.1007/s10456-021-09819-0
Abstract: Several B-cell subsets with distinct functions and polarized cytokine profiles that extend beyond antibody production have been reported in different cancers. Here we have demonstrated that proliferating B cells were predominantly found in the peritumoral… read more here.
Keywords: esophageal squamous; cell carcinoma; squamous cell; escc ... See more keywords
Immunostaining of telomerase in embryonic and juvenile feather follicle of the chick labels proliferating cells for feather formation.
Sign Up to like & getrecommendations! Published in 2020 at "Zoology"
DOI: 10.1016/j.zool.2020.125846
Abstract: Feathers regenerate through proliferation of cells derived from follicle stem cells. Immunoloblotting for telomerase in chick embryonic and juvenile feathers shows immunopositive bands around 100 kDa, 75 and 60 kDa only in embryonic feathers, indicating… read more here.
Keywords: chick; embryonic juvenile; follicle; proliferating cells ... See more keywords
Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer
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DOI: 10.1038/onc.2017.36
Abstract: Increased glucose consumption is a hallmark of cancer cells. The increased consumption and subsequent metabolism of glucose during proliferation creates the need for a constant supply of NAD, a co-factor in glycolysis. Regeneration of the… read more here.
Keywords: glycolysis; cytosolic malate; proliferating cells; cancer ... See more keywords
PD‐1‐induced proliferating T cells exhibit a distinct transcriptional signature
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DOI: 10.1111/imm.13388
Abstract: Ligation of the inhibitory receptor PD‐1 on T cells results in the inhibition of numerous cellular functions. Despite the overtly inhibitory outcome of PD‐1 signalling, there are additionally a collection of functions that are activated.… read more here.
Keywords: distinct transcriptional; induced proliferating; exhibit distinct; proliferating cells ... See more keywords
6-mercaptopurine promotes energetic failure in proliferating T cells
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DOI: 10.18632/oncotarget.17889
Abstract: The anticancer drug 6-mercaptopurine (6-MP) inhibits de novo purine synthesis and acts as an antiproliferative agent by interfering with protein, DNA and RNA synthesis and promoting apoptosis. Metabolic reprogramming is crucial for tumor progression to… read more here.
Keywords: promotes energetic; mercaptopurine promotes; energetic failure; proliferating cells ... See more keywords
An Engineered Mouse to Identify Proliferating Cells and Their Derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00388
Abstract: Background Cell proliferation is a fundamental event during development, disease, and regeneration. Effectively tracking and quantifying proliferating cells and their derivatives is critical for addressing many research questions. Cell cycle expression such as for Ki67,… read more here.
Keywords: cells derivatives; cell proliferation; proliferating cells; cre ... See more keywords