GFPT1 promotes the proliferation of cervical cancer via regulating the ubiquitination and degradation of PTEN.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac073
Abstract: Cervical cancer demonstrates the fourth incidence and death rate in female worldwide. Glutamine--fructose-6-phosphate transaminase 1 (GFPT1), the first rate-limited enzyme of hexosamine biosynthesis pathway, has been reported to promote the progression of cancers. However, the… read more here.
Keywords: cervical cancer; proliferation cervical; ubiquitination degradation; gfpt1 ... See more keywords
TRIM31 acts as an intermediate molecule in the process by which Snai2 impairs the proliferation of cervical cancer cells
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1537991
Abstract: Snai2 is a transcription factor that inhibits the proliferation of cervical cancer cells and tumor growth. The expression of Snai2 inhibited the expression of β-catenin and impaired Wnt/β-catenin signaling pathway activity. The results of the… read more here.
Keywords: proliferation cervical; cancer cells; cervical cancer; trim31 ... See more keywords