Down-regulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of STAT1 in endometriosis.
Sign Up to like & getrecommendations! Published in 2022 at "Biology of reproduction"
DOI: 10.1093/biolre/ioac081
Abstract: BACKGROUND Endometriosis is a benign gynecologic disease that causes chronic pelvic pain, dysmenorrhea and infertility and shares several characteristics with malignant tumors, afflicting women of reproductive age. Hexokinase 2 (HK2) plays an essential role as… read more here.
Keywords: hk2; proliferation endometrial; endometriosis; stromal cells ... See more keywords
Effects of Inhibitors of the Activity of the Circulating Renin–Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells
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DOI: 10.3390/ijms262210968
Abstract: Endometrial cancers increase expression of the renin–angiotensin system (RAS). This study aimed to determine if inhibiting the RAS would reduce the viability and proliferation of endometrial cancer cells. The expression of RAS genes was measured… read more here.
Keywords: angiotensin system; proliferation endometrial; angiotensin; renin angiotensin ... See more keywords