Circ_0123996 promotes the proliferation, inflammation, and fibrosis of mesangial cells by sponging miR‐203a‐3p to upregulate SOX6 in diabetic nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23139
Abstract: Circular RNA has been reported to participate in human diseases including diabetic nephropathy (DN). However, the role and mechanism of circ_0123996 in DN need to be further explored. Relative expression levels of circ_0123996, microRNA (miR)‐203a‐3p,… read more here.
Keywords: mir 203a; proliferation inflammation; inflammation fibrosis; circ 0123996 ... See more keywords
MK2206 attenuates atherosclerosis by inhibiting lipid accumulation, cell migration, proliferation, and inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00729-x
Abstract: Cardiovascular disease is a common comorbidity in patients with cancer, and the main leading cause of noncancer-related deaths in cancer survivors. Considering that current antitumor drugs usually induce cardiovascular injury, the quest for developing new… read more here.
Keywords: migration proliferation; lipid accumulation; inflammation; proliferation ... See more keywords
Long intergenic non-coding RNA -00917 regulates the proliferation, inflammation, and pyroptosis of nucleus pulposus cells via targeting miR-149-5p/NOD-like receptor protein 1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2043100
Abstract: ABSTRACT Intervertebral disc degeneration (IDD) has caused great trouble in people’s lives. Dysregulated long noncoding RNAs (lncRNAs) are closely linked to IDD progression. Our study aims to analyze the role of LINC00917 in the progression… read more here.
Keywords: pyroptosis; mir 149; nucleus pulposus; pulposus cells ... See more keywords
Protein Arginine Methyltransferase 2 Inhibits Angiotensin II-Induced Proliferation and Inflammation in Vascular Smooth Muscle Cells
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DOI: 10.1155/2018/1547452
Abstract: Objectives Protein arginine methyltransferase 2 (PRMT2) protects against vascular injury-induced intimal hyperplasia; however, little is known about the role of PRMT2 in angiotensin II (Ang II)-induced VSMCs proliferation and inflammation. This research aims to determine… read more here.
Keywords: prmt2; ang induced; proliferation inflammation; proliferation ... See more keywords
KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation response.
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DOI: 10.1691/ph.2022.1970
Abstract: Psoriasis is a complex chronic skin inflammatory disease characterized by abnormal proliferation, differentiation of keratinocytes and infiltration of lymphocytes and neutrophils. The tripeptide KdPT, structurally derived from the C-terminal amino acid of alpha-melanocyte-stimulating hormone, has… read more here.
Keywords: proliferation; inhibiting proliferation; induced psoriasis; psoriasis ... See more keywords