Hypermethylation of the PZP gene is associated with hepatocellular carcinoma cell proliferation, invasion and migration
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DOI: 10.1002/2211-5463.13093
Abstract: Pregnancy zone protein (PZP), a member of the proteinase inhibitor I39 (‐2‐macroglobulin) family of proteins, is involved in the initiation and development of various tumors. The gene encoding PZP is hypermethylated and expressed at low… read more here.
Keywords: hepatocellular carcinoma; carcinoma; proliferation invasion; hcc ... See more keywords
Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway
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DOI: 10.1002/cam4.2719
Abstract: Cholangiocarcinoma is a malignant tumor originating from bile duct epithelium. Currently, the treatment strategy is very limited and the prognosis is poor. Recent studies reported celastrol exhibits antigrowth and antimetastasis properties in many tumors. Our… read more here.
Keywords: proliferation invasion; celastrol inhibition; cholangiocarcinoma; antitumor activity ... See more keywords
Exosome‐transmitted linc00852 associated with receptor tyrosine kinase AXL dysregulates the proliferation and invasion of osteosarcoma
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DOI: 10.1002/cam4.3303
Abstract: Receptor tyrosine kinase AXL has been found to be highly expressed in osteosarcoma and positively associated with poor prognosis. There are tumor groups with high or low AXL expression, which had different capabilities of invading… read more here.
Keywords: exosome transmitted; proliferation invasion; kinase axl; receptor tyrosine ... See more keywords
hsa‐mir‐133a‐2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3‐mediated PI3K/ATK pathway
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DOI: 10.1002/cam4.5380
Abstract: Cervical cancer, one of the common types of malignant tumors progressed in women, is on the rise in developing countries. Numerous previous studies have demonstrated that hsa‐mir‐133a‐2 miRNA is abnormally expressed in cervical cancer cells.… read more here.
Keywords: cervical cancer; cancer; proliferation invasion; hsa mir ... See more keywords
miR‐802 inhibits the proliferation, invasion, and epithelial‐mesenchymal transition of glioblastoma multiforme cells by directly targeting SIX4
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DOI: 10.1002/cbf.3451
Abstract: It is well known that the sine oculis homeobox 4 (SIX4) expression is very relevant to the progression of multiple cancers. Moreover, we found that miR‐802 could directly target the SIX4. However, the precise mechanism… read more here.
Keywords: gbm; mir 802; proliferation invasion; six4 ... See more keywords
LncRNA CRNDE is activated by SP1 and promotes osteosarcoma proliferation, invasion, and epithelial‐mesenchymal transition via Wnt/β‐catenin signaling pathway
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DOI: 10.1002/jcb.29607
Abstract: Long noncoding RNAs (lncRNAs) were identified as a vital part in the development and progression of cancer in recent years. Colorectal neoplasia differentially expressed (CRNDE), a lncRNA, functions as an oncogene in some malignant neoplasias,… read more here.
Keywords: wnt catenin; crnde; proliferation invasion; lncrna crnde ... See more keywords
Hsa_circ_0001982 promotes the proliferation, invasion, and multidrug resistance of osteosarcoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24493
Abstract: Osteosarcoma (OS) is the most common bone cancer mostly seen in people aged 10–25 years. This research aims to clarify the function of hsa_circ_0001982 in osteosarcoma (OS) and its effect on drug resistance, preliminarily exploring its… read more here.
Keywords: circ 0001982; proliferation invasion; hsa circ; resistance ... See more keywords
The long noncoding RNA uc.294 is upregulated in early‐onset pre‐eclampsia and inhibits proliferation, invasion of trophoblast cells (HTR‐8/SVneo)
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DOI: 10.1002/jcp.27916
Abstract: Recently, a large number of long noncoding RNAs (lncRNAs) have been reported in human diseases that are evolutionarily conserved and are likely to play a role in many biological events including pre‐eclampsia. In our previous… read more here.
Keywords: pre eclampsia; onset pre; early onset; proliferation invasion ... See more keywords
Modulation of Myb‐induced NF‐kB ‐STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors
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DOI: 10.1002/jcp.28715
Abstract: c‐Myb regulates tumorigenesis in multiple cancers. Here we show, for the first time, the mechanism of c‐Myb‐mediated proliferation, invasion, and drug resistance in ovarian cancer (OC), the most lethal gynecological cancer, and a comparative analyses… read more here.
Keywords: resistance ovarian; proliferation invasion; ovarian cancer; myb ... See more keywords
LINC00449 regulates the proliferation and invasion of acute monocytic leukemia and predicts favorable prognosis
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DOI: 10.1002/jcp.29487
Abstract: Acute myeloid leukemia (AML) is a highly aggressive disease that causes high mortality. Long noncoding RNA (lncRNA) have studied in recent years that could be a potential biomarker and therapeutic target. Therefore, it is urgently… read more here.
Keywords: proliferation invasion; target; linc00449; leukemia ... See more keywords
Exportin‐T promotes tumor proliferation and invasion in hepatocellular carcinoma
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DOI: 10.1002/mc.22928
Abstract: Exportin‐T (XPOT) belongs to the RAN‐GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Up‐regulation of XPOT indicates poor prognosis in breast cancer patients. However, the correlation between XPOT and… read more here.
Keywords: hepatocellular carcinoma; proliferation invasion; proliferation; tumor proliferation ... See more keywords