Inhibition of miR-135a-5p attenuates vascular smooth muscle cell proliferation and vascular remodeling in hypertensive rats.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-020-00608-x
Abstract: Proliferation of vascular smooth muscle cells (VSMCs) greatly contributes to vascular remodeling in hypertension. This study is to determine the roles and mechanisms of miR-135a-5p intervention in attenuating VSMC proliferation and vascular remodeling in spontaneously… read more here.
Keywords: proliferation; vsmc proliferation; shrs; vascular remodeling ... See more keywords
ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale Research Letters"
DOI: 10.1186/s11671-017-2097-6
Abstract: The proliferation of vascular smooth muscle cells (VSMCs) is one of the key events during the progress of atherosclerosis. The activated liver X receptor (LXR) signalling pathway is demonstrated to inhibit platelet-derived growth factor BB… read more here.
Keywords: t0901317; vascular smooth; proliferation; smooth muscle ... See more keywords
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H2S in Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Aging and Disease"
DOI: 10.14336/ad.2021.1104
Abstract: Tissue ischemia and hypoxia caused by the abnormal proliferation of smooth muscle cells (SMCs) in the diabetic state is an important pathological basis for diabetic microangiopathy. Studies in recent years have shown that the chronic… read more here.
Keywords: muscle cells; proliferation; proliferation vascular; h2s ... See more keywords
High dose insulin promotes the proliferation of vascular smooth muscle cells via AP-1/ SM-α pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/21-201-a
Abstract: Proliferation of vascular smooth muscle cells (VSMCs) participates in multiple cardiovascular disorders, while the mechanism remains unclear. This study aims to investigate the effects of insulin on VSMC. Insulin was used to stimulate rat VSMCs,… read more here.
Keywords: vascular smooth; proliferation vascular; muscle cells; insulin ... See more keywords
Proliferation of vascular smooth muscle cells under inflammation is regulated by NF-κB p65/microRNA-17/RB pathway activation
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2017.3212
Abstract: Inflammation and excessive proliferation of vascular smooth muscle cells (VSMCs) have key roles in various vascular disorders, including restenosis, atherosclerosis and pulmonary artery hypertension. However, the underlying mechanism remains unclear. The present study investigated the… read more here.
Keywords: vascular smooth; inflammation; proliferation; proliferation vascular ... See more keywords