Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105105
Abstract: VEGF/VEGFR2 pathway is the crucial therapeutic target in the treatment of cancer. So that, a new series of quinoxaline-2(1H)-one derivatives were designed and synthesized. The synthesized compounds were tested against three human cancer cell lines… read more here.
Keywords: anti proliferative; hct 116; cell lines; quinoxaline one ... See more keywords
Assessment of free radical scavenging and anti-proliferative activities of Tinospora cordifolia Miers (Willd)
Sign Up to like & getrecommendations! Published in 2017 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-1953-3
Abstract: BackgroundTinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes, cancer and skin disease… read more here.
Keywords: medicine; anti proliferative; assessment free; activity ... See more keywords
Methanolic extract of Euchelus asper exhibits in-ovo anti-angiogenic and in vitro anti-proliferative activities
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DOI: 10.1186/s40659-017-0147-2
Abstract: BackgroundThe marine environment is a rich source of bioactive natural products. Many of the marine bioactive compounds have been derived successfully from molluscs. Euchelus asper is a marine mollusc which is commonly found in the… read more here.
Keywords: methanolic extract; anti proliferative; euchelus asper; extract euchelus ... See more keywords
Synthesis and In Vitro Anti-proliferative Activities on LNCaP, LS180 and MKN45 of Novel 20(R)-Panaxadiol Derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666230412095428
Abstract: AIMS 20(R)-Panaxadiol (20(R)-PD) can inhibit tumor proliferation. Three series of novel 20(R)-PD derivatives were synthesized by modifying the A-ring. BACKGROUND 20(R)-PD, a tetracyclic triterpenoid, is a non-natural saponin present in the form of protopanaxadiol. Because… read more here.
Keywords: lncap ls180; ls180 mkn45; vitro anti; anti proliferative ... See more keywords