Development of Proliferative Response of Thymic Lymphocytes to T-Cell Mitogen in Rats Exposed to Endocrine Disrupter DDT during Ontogeny
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-020-04824-7
Abstract: We studied the formation of proliferative response of thymic lymphocytes to T-cell mitogen in rats exposed to endocrine disrupter DDT during prenatal and postnatal ontogeny. Developmental exposure to the endocrine disruptor was found to attenuate… read more here.
Keywords: thymic lymphocytes; response; proliferative response; endocrine disrupter ... See more keywords
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity
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DOI: 10.1038/s41467-020-15552-x
Abstract: It is unclear why some tissues are refractory to the mitogenic effects of the oncogene Myc. Here we show that Myc activation induces rapid transcriptional responses followed by proliferation in some, but not all, organs. Despite… read more here.
Keywords: transcription; heart; show myc; proliferative response ... See more keywords
Selective proliferative response of microglia to alternative polarization signals
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DOI: 10.1186/s12974-017-1011-6
Abstract: BackgroundMicroglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and immune defense. Under the influence of endogenous or pathological signals, microglia undertake… read more here.
Keywords: response microglia; proliferative response; polarization; proliferation ... See more keywords