Overexpression of gene encoding the key enzyme involved in proline-biosynthesis (PuP5CS) to improve salt tolerance in switchgrass (Panicum virgatum L.)
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DOI: 10.1007/s00299-018-2304-7
Abstract: Key messageGenetic improvement through overexpressing PuP5CS in switchgrass is feasible for enhancing plant salt stress tolerance.AbstractSwitchgrass (Panicum virgatum L.) has developed into a dedicated bioenergy crop. To improve the biomass production of switchgrass grown on… read more here.
Keywords: tolerance; switchgrass; salt tolerance; panicum virgatum ... See more keywords
Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure
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DOI: 10.1038/s41598-020-80917-7
Abstract: Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functionally linked… read more here.
Keywords: glutamate levels; meth exposure; glutamate homeostasis; exposure ... See more keywords
Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis
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DOI: 10.1080/15548627.2022.2093026
Abstract: ABSTRACT Cancer-associated fibroblasts (CAFs) are considered one of the most critical stromal cells that interact with pancreatic ductal adenocarcinoma (PDAC) and promote tumor growth, metastasis, and treatment resistance. Previous studies illustrated macroautophagy/autophagy contributes to CAF… read more here.
Keywords: activation; cancer associated; proline biosynthesis; cancer ... See more keywords