Efficacy of Hydroxy-L-proline (HYP) analogs in the treatment of primary hyperoxaluria in Drosophila Melanogaster
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DOI: 10.1186/s12882-018-0980-8
Abstract: BackgroundSubstrate reduction therapy with analogs reduces the accumulation of substrates by inhibiting the metabolic pathways involved in their biosynthesis, providing new treatment options for patients with primary hyperoxalurias (PHs) that often progress to end-stage renal… read more here.
Keywords: hyp analogs; melanogaster; proline hyp; hydroxy proline ... See more keywords