The Effects of Proline Isomerization on the Solvation Behavior of Elastin-Like Polypeptides in Water-Ethanol Mixtures.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202100907
Abstract: Elastin-like polypeptides (ELPs) are well-known proline-rich stimulus-responsive polymers. They have broad applications ranging from drug delivery to green chemistry. Recently we have shown that the cis/trans proline isomerization can be used to regulate their conformational… read more here.
Keywords: behavior; water; isomerization; proline isomerization ... See more keywords
Static and Dynamic Roles of Proteins in Proline Isomerization Reactions
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DOI: 10.1016/j.bpj.2016.11.2696
Abstract: The molecular mechanism of enzyme catalysis has been of great interest in protein studies. While the catalytic role of amino acids in enzymes at the transition states has been of great interest, and have been… read more here.
Keywords: proline isomerization; transition; isomerization; isomerization reactions ... See more keywords
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war
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DOI: 10.1038/s41467-020-19844-0
Abstract: Catalysis of cis/trans isomerization of prolines is important for the activity and misfolding of intrinsically disordered proteins. Catalysis is achieved by peptidylprolyl isomerases, a superfamily of molecular chaperones. Here, we provide atomic insight into a… read more here.
Keywords: proline isomerization; molecular chaperone; activity; catalysis ... See more keywords