Articles with "prolinol aryl" as a keyword



Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors

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Published in 2020 at "Psychopharmacology"

DOI: 10.1007/s00213-020-05536-6

Abstract: Rationale Prolinol aryl ethers and their rigidified analogues pyrrolidinyl benzodioxanes have a high affinity for mammalian α4β2 nicotinic acetylcholine receptors (nAChRs). Electrophysiological studies have shown that the former are full agonists and the latter partial… read more here.

Keywords: aryl ethers; high affinity; prolinol aryl; agonist ... See more keywords