Revefenacin, a Long‐Acting Muscarinic Antagonist, Does Not Prolong QT Interval in Healthy Subjects: Results of a Placebo‐ and Positive‐Controlled Thorough QT Study
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.732
Abstract: Revefenacin is a novel once‐daily, lung‐selective, long‐acting muscarinic antagonist developed as a nebulized inhalation solution for the maintenance treatment of chronic obstructive pulmonary disease. In a randomized, 4‐way crossover study, healthy subjects received a single… read more here.
Keywords: muscarinic antagonist; long acting; prolong interval; healthy subjects ... See more keywords
Does infection prolong the QT interval?
Sign Up to like & getrecommendations! Published in 2020 at "Internal Medicine Journal"
DOI: 10.1111/imj.14741
Abstract: The corrected QT (QTc) interval is a strong predictor of ischaemic heart disease and cardiovascular mortality. It may trigger lethal arrhythmias and sudden death. Risk factors include electrolyte disorders, medications, prior cardiovascular disease and genetic… read more here.
Keywords: infection prolong; prolong interval;