Delineation of clinical course, outcomes, and prognostic factors in patients with T‐cell prolymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26918
Abstract: T‐cell prolymphocytic leukemia (T‐PLL) is a rare, post‐thymic T‐cell neoplasm with a diverse clinical course. T‐PLL is typically associated with a poor prognosis; however, a subset of patients have inactive disease on initial presentation. There… read more here.
Keywords: prognostic factors; disease; clinical course; course ... See more keywords
GvL effects in T-prolymphocytic leukemia: evidence from MRD kinetics and TCR repertoire analyses
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DOI: 10.1038/bmt.2016.305
Abstract: Allogeneic stem cell transplantation (alloSCT) is used for treating patients with T-prolymphocytic leukemia (T-PLL). However, direct evidence of GvL activity in T-PLL is lacking. We correlated minimal residual disease (MRD) kinetics with immune interventions and… read more here.
Keywords: mrd; mrd kinetics; evidence; prolymphocytic leukemia ... See more keywords
CD161 Is Expressed in a Subset of T-Cell Prolymphocytic Leukemia Cases and Is Useful for Disease Follow-up.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqz060
Abstract: OBJECTIVES CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in… read more here.
Keywords: cd161; disease; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
Comparison of clinicopathological characteristics between T‐cell prolymphocytic leukemia and peripheral T‐cell lymphoma, not otherwise specified
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Haematology"
DOI: 10.1111/ejh.12856
Abstract: T‐cell prolymphocytic leukemia (T‐PLL) is a very rare, aggressive T‐cell neoplasm. Peripheral T‐cell lymphoma, not otherwise specified (PTCL‐NOS) is also a highly aggressive lymphoma. These two diseases can often be confused with each other; therefore,… read more here.
Keywords: lymphoma; cell prolymphocytic; prolymphocytic leukemia; cell ... See more keywords
Mutations in PIGA cause a CD52‐/GPI‐anchor‐deficient phenotype complicating alemtuzumab treatment in T‐cell prolymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Haematology"
DOI: 10.1111/ejh.13511
Abstract: Infusional alemtuzumab followed by consolidating allogeneic hematopoietic stem cell transplantation in eligible patients is considered a standard of care in T‐cell prolymphocytic leukemia (T‐PLL). Antibody selection against CD52 has been associated with the development of… read more here.
Keywords: cd52; cell prolymphocytic; mutations piga; prolymphocytic leukemia ... See more keywords
Generalized pruritic dark papules in a patient with T‐cell prolymphocytic leukemia – a clinicopathological challenge
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Dermatology"
DOI: 10.1111/ijd.14642
Abstract: A 48-year-old man presented with multiple pruritic dark red papules for 9 months. The lesions started on his hands and subsequently spread to the trunk and limbs within the last 2 months. He also had… read more here.
Keywords: pruritic dark; blood; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
Non-canonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-1908
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a chemotherapy-refractory T-cell malignancy with limited therapeutic options and a poor prognosis. Current disease concepts implicate TCL1A oncogene-mediated enhanced T-cell receptor (TCR) signaling and aberrant DNA repair as central perturbed… read more here.
Keywords: cell; ago2; non canonical; cell prolymphocytic ... See more keywords
Recurrence of T-Cell Prolymphocytic Leukemia With a Rare Presentation as Diffuse Generalized Skin Lesion
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DOI: 10.1177/23247096231176223
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm that originates from mature post-thymic T-cells. Cutaneous manifestations are a common presentation in T-PLL but rarely are a presentation in the recurrent setting. Here, we… read more here.
Keywords: prolymphocytic leukemia; pll; cell prolymphocytic; diffuse ... See more keywords
T-cell prolymphocytic leukemia negative for surface CD3 and CD45.
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-03-840611
Abstract: ![Figure][1] A 75-year-old man was referred to us with an outside diagnosis of T-cell prolymphocytic leukemia (T-PLL) posttreatment. He had mild leukocytosis (white blood cell count, 11.5 × 109/L) and multicompartmental lymphadenopathy by positron emission… read more here.
Keywords: cell; negative surface; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
T-cell prolymphocytic leukemia presenting as ascites.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019001033
Abstract: ![Figure][1] A 77-year-old woman presented with abdominal discomfort, fatigue, and dyspnea. She had a history of colorectal cancer. Physical examination revealed a tense, distended abdomen and splenomegaly. Routine peripheral blood (PB) examination showed thrombocytopenia (107… read more here.
Keywords: cell prolymphocytic; presenting ascites; leukemia presenting; prolymphocytic leukemia ... See more keywords
Comparative analysis of characteristics, survival trends, and associated malignancies of B-cell and T-cell prolymphocytic leukemia: A surveillance, epidemiology, and end results (SEER) based study1998 to 2016.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.7558
Abstract: 7558Background: Prolymphocytic leukemia (PLL) compromises two subsets; B-cell and T-cell, accounting for less than 2% of mature lymphocytic leukemia. Both of them are rare lymphoid neoplasms with a... read more here.
Keywords: comparative analysis; analysis characteristics; epidemiology; prolymphocytic leukemia ... See more keywords