Prominin‐1 Promotes Biliary Fibrosis Associated With Biliary Atresia
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DOI: 10.1002/hep.30550
Abstract: In patients with biliary atresia (BA), the extent of intrahepatic biliary fibrosis negatively correlates with successful surgical bypass of the congenital cholangiopathy as well as subsequent transplant‐free survival. We recently linked the expansion of a… read more here.
Keywords: biliary fibrosis; fibrosis; prom1; prominin ... See more keywords
TWEAK/FN14 promotes profibrogenic pathway activation in Prominin-1-expressing hepatic progenitor cells in biliary atresia
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DOI: 10.1097/hep.0000000000000026
Abstract: Background and Aims: Biliary atresia (BA), a congenital cholestatic liver disease, commonly culminates in end-stage liver disease. We previously demonstrated in BA that Prominin-1 (Prom1)-expressing hepatic progenitor cells (HPCs) expand within regions of developing fibrosis,… read more here.
Keywords: prom1; tweak; fn14; ductular reactions ... See more keywords