Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06195-5
Abstract: Background Many anti-nausea treatments are available for chronic gastrointestinal syndromes, but data on efficacy and comparative effectiveness are sparse. Aims To conduct a sectional survey study of patients with chronic nausea to assess comparative effectiveness… read more here.
Keywords: marijuana; nausea treatments; effective treatments; nausea ... See more keywords
AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108888
Abstract: Relapse and drug resistance is still major challenges in the treatment of leukemia. Promethazine, an antihistaminic phenothiazine derivative, has been used to prevent chemotherapy-induced emesis, although there is no report about its antitumor potential. Thus,… read more here.
Keywords: myeloid leukemia; autophagy associated; chronic myeloid; activation ... See more keywords
Promethazine improves antibiotic efficacy and disrupts biofilms of Burkholderia pseudomallei
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DOI: 10.1080/08927014.2016.1262846
Abstract: Abstract Efflux pumps are important defense mechanisms against antimicrobial drugs and maintenance of Burkholderia pseudomallei biofilms. This study evaluated the effect of the efflux pump inhibitor promethazine on the structure and antimicrobial susceptibility of B.… read more here.
Keywords: pseudomallei biofilms; efficacy; promethazine improves; biofilm ... See more keywords
Effect of promethazine on biofilms of gram-positive cocci associated with infectious endocarditis
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DOI: 10.1080/08927014.2023.2202313
Abstract: Abstract This study evaluated the antimicrobial activity of promethazine against Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus mutans and its effect on the antimicrobial susceptibility of biofilms grown in vitro and ex vivo on porcine heart… read more here.
Keywords: biofilms gram; effect; positive cocci; biofilms ... See more keywords
Acute onset of orofacial dystonia from promethazine treatment
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DOI: 10.1097/md.0000000000017675
Abstract: Abstract Rationale: Promethazine is an antihistamine agent used commonly for nausea and allergy. Along with its anticholinergic and antidopaminergic functions, promethazine is also used for psychiatric symptoms, such as troubling sleep, anxiety, and agitation. Previous… read more here.
Keywords: acute onset; promethazine; dystonia; promethazine treatment ... See more keywords
Development and Validation of a High-Performance Liquid Chromatography–Tandem Mass Spectrometry Method to Determine Promethazine and Its Metabolites in Edible Tissues of Swine
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DOI: 10.3390/foods12112180
Abstract: This study aimed to determine promethazine (PMZ) and its metabolites, promethazine sulfoxide (PMZSO) and monodesmethyl-promethazine (Nor1PMZ), in swine muscle, liver, kidney, and fat. A sample preparation method and high-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis… read more here.
Keywords: performance liquid; liquid chromatography; method; promethazine ... See more keywords