Promiscuous enzymes cooperate at the substrate level en route to lactazole A.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c05541
Abstract: Enzymes involved in biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) often have relaxed specificity profiles and are able to modify diverse substrates. When several such enzymes act together during precursor peptide maturation, a… read more here.
Keywords: biosynthesis; formation; level; promiscuous enzymes ... See more keywords
Promiscuous Enzymes Cause Biosynthesis of Diverse Siderophores in Shewanella oneidensis
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DOI: 10.1128/aem.00030-20
Abstract: The simultaneous production of multiple siderophores is considered a general strategy for microorganisms to rapidly adapt to their ever-changing environments. In this study, we show that some Shewanella spp. may downscale their capability for siderophore… read more here.
Keywords: synthesis; siderophore; oneidensis; multiple siderophores ... See more keywords