Tetrahydroacridine derivative and its conjugate with gold nanoparticles: Promising agents for the treatment of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2023 at "Physical Chemistry Chemical Physics"
DOI: 10.1039/d3cp00767g
Abstract: A new tetrahydroacridine derivative (CHDA) with acetylcholinesterase inhibitory properties was synthesized. Using a range of physicochemical techniques, it was shown that the compound strongly adsorbs onto the surface of planar... read more here.
Keywords: conjugate gold; gold nanoparticles; nanoparticles promising; tetrahydroacridine derivative ... See more keywords
Therapeutic strategies for Parkinson’s disease: promising agents in early clinical development
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2020.1814252
Abstract: ABSTRACT Introduction To date, no drug has demonstrated clinically indisputable neuroprotective efficacy in Parkinson’s disease (PD). We also have no effective symptomatic treatment for disabling symptoms such as balance problems, and dementia, and we need… read more here.
Keywords: therapeutic strategies; strategies parkinson; parkinson disease; promising agents ... See more keywords
An Update on Promising Agents against COVID-19: Secondary Metabolites and Mechanistic Aspects.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220722124826
Abstract: BACKGROUND Coronavirus disease 2019 (COVID‑19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and is associated with a high level of mortality. OBJECTIVE This updated review aims to present the most important traditional medicinal… read more here.
Keywords: promising agents; secondary metabolites; update promising; medicinal plants ... See more keywords
Potential Therapeutic Targets and Promising Agents for Combating NAFLD
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10040901
Abstract: Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), is a growing cause of liver cirrhosis and liver cancer worldwide because of the global increases in obesity, dyslipidemia, hypertension, and type 2 diabetes mellitus. Contrary… read more here.
Keywords: agents combating; promising agents; targets promising; combating nafld ... See more keywords
Chemosensing Properties of Coumarin Derivatives: Promising Agents with Diverse Pharmacological Properties, Docking and DFT Investigation
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DOI: 10.3390/molecules27185921
Abstract: In this work, a three-component reaction of 3-acetyl-4-hydroxycoumarine, malononitrile, or cyanoacetate in the presence of ammonium acetate was used to form coumarin derivatives. The chemical structures of new compounds were identified by 1H, 13C NMR… read more here.
Keywords: derivatives promising; properties coumarin; promising agents; coumarin derivatives ... See more keywords
Citroflavonoids as Promising Agents for Drug Discovery in Diabetes and Hypertension: A Systematic Review of Experimental Studies
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227933
Abstract: Flavonoids are naturally occurring compounds widely distributed in the Citrus genus. These natural compounds have many health benefits, mainly for metabolic and cardiovascular diseases. In fact, some these compounds are components of drug products with… read more here.
Keywords: citroflavonoids promising; promising agents; diabetes hypertension; drug ... See more keywords