Decision making for promising quinoline‐based anticancer agents through combined methodology
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22522
Abstract: During the development of effective drugs for the treatment of cancer, one of the most important tasks is to identify effective drug candidates having maximum antiproliferation and minimum side effects. This paper considers the problem… read more here.
Keywords: methodology; anticancer agents; decision making; anticancer ... See more keywords
Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23206
Abstract: Natural products serve as the single most productive source for the discovery of drugs and pharmaceutical leads. Among the various chemicals derived from microbes, plants, and animals, phytochemicals have emerged as potential candidates for the… read more here.
Keywords: anticancer drug; natural promising; drug current; promising anticancer ... See more keywords
Potential and promising anticancer drugs from adenosine and its analogs.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.02.020
Abstract: In recent years, many studies have shown that adenosine has efficacy for treating cancer. More importantly, some adenosine analogs have been successfully marketed to fulfill anticancer purposes. In this review, we summarize the anticancer effects… read more here.
Keywords: potential promising; drugs adenosine; anticancer drugs; adenosine analogs ... See more keywords
Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2020.111289
Abstract: The preparation of two new Ru(II)/diphosphine complexes containing Lapachol (Lap) and Lawsone (Law): (1) [Ru(Lap)(dppm)2]PF6 and (2) [Ru(Law)(dppm)2]PF6, where dppm = bis(diphenylphosphino)methane, is reported here. The complexes were synthetized and fully characterized by elemental analyses, molar conductivity,… read more here.
Keywords: mda 231; new ruthenium; diphosphine; lapachol ... See more keywords
Karonudib is a promising anticancer therapy in hepatocellular carcinoma
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DOI: 10.1177/1758835919866960
Abstract: Background: Hepatocellular carcinoma (HCC) is the most common form of liver cancer and is generally caused by viral infections or consumption of mutagens, such as alcohol. While liver transplantation and hepatectomy is curative for some… read more here.
Keywords: hepatocellular carcinoma; karonudib promising; hcc; mth1 ... See more keywords
β-lapachone: a promising anticancer agent with a unique NQO1 specific apoptosis in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Current cancer drug targets"
DOI: 10.2174/1568009622666220427121127
Abstract: Cancer, one of the major health problems all over the world, requires more competent drugs for clinical use. One recent possible chemotherapeutic drug under research is β-lapachone. β-lapachone (1,2-naphthoquinone) has promising activity against those tumors… read more here.
Keywords: anticancer agent; pancreatic cancer; lapachone promising; promising anticancer ... See more keywords
Screening and in vitro Biological Evaluation of Novel Multiple Tyrosine Kinases Inhibitors as Promising Anticancer Agents.
Sign Up to like & getrecommendations! Published in 2023 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666230403104816
Abstract: BACKGROUND Tyrosine kinases have emerged as key stimulatory drivers in several cancer-related pathways. This is particularly evident in non-small cell lung cancer with regulating cell growth and apoptosis and so on. Tyrosine kinase inhibitors (TKI)… read more here.
Keywords: tyrosine; tyrosine kinases; promising anticancer; anticancer agents ... See more keywords
Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms
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DOI: 10.3389/fchem.2023.1164477
Abstract: Spermidine is a naturally occurring polyamine compound found in semen. It is also found in several plant sources and boasts a remarkable biological profile, particularly with regards to its anticancer properties. Spermidine specifically interferes with… read more here.
Keywords: anticancer agent; mechanisms spermidine; agent recent; promising anticancer ... See more keywords
Lithium: A Promising Anticancer Agent
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DOI: 10.3390/life13020537
Abstract: Lithium is a therapeutic cation used to treat bipolar disorders but also has some important features as an anti-cancer agent. In this review, we provide a general overview of lithium, from its transport into cells,… read more here.
Keywords: promising anticancer; agent; lithium; lithium promising ... See more keywords