Recent advances in targeted nanomedicine as promising antitumor therapeutics.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.09.031
Abstract: A tumor serves as a major avenue in drug development owing to its complexity. Conventional therapies against tumors possess limitations such as suboptimal therapeutic efficacy and extreme side effects. These display poor pharmacokinetics and lack… read more here.
Keywords: promising antitumor; antitumor therapeutics; advances targeted; nanomedicine promising ... See more keywords
Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3
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DOI: 10.1038/onc.2017.270
Abstract: Signal transducer and activator of transcription 3(STAT3) is an emerging target for cancer therapy. In this study, we identify Toosendanin (TSN) is an effective inhibitor of STAT3, leading to the impediment of various oncogenic processes… read more here.
Keywords: antitumor efficacy; promising antitumor; toosendanin demonstrates; efficacy osteosarcoma ... See more keywords
Terpyridines as promising antitumor agents: an overview of their discovery and development
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DOI: 10.1080/17460441.2022.2017877
Abstract: ABSTRACT Introduction The fused aromatic system of terpyridines makes them good, innocent ligands for various metals. The resulting complexes have been extensively studied for both their biological activity and physico-chemical properties. However, although free ligands… read more here.
Keywords: agents overview; promising antitumor; discovery; activity ... See more keywords