Organogels, promising drug delivery systems: an update of state‐of‐the‐art and recent applications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.12.019
Abstract: ABSTRACT Organogels are semi‐solid systems with an organic liquid phase immobilized by a three‐dimensional network composed of self‐assembled, crosslinked or entangled gelator fibers. Organogel applications are various, including chemistry, pharmaceuticals, cosmetics, biotechnologies and food technology.… read more here.
Keywords: organogels promising; drug delivery; delivery; delivery systems ... See more keywords
Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications
Sign Up to like & getrecommendations! Published in 2021 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2021.1931302
Abstract: Abstract A global threat has emerged in 2019 due to the rapid spread of Coronavirus disease (COVID-19). As of January 2021, the number of cases worldwide reached 103 million cases and 2.22 million deaths which… read more here.
Keywords: storm; drug repurposing; promising drug; cytokine storm ... See more keywords
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15000
Abstract: Tetramethylpyrazine (TMP) was originally isolated from the traditional Chinese herb ligusticum and the fermented Japanese food natto and has since been synthesized. TMP has a long history of beneficial effects in the treatment of many… read more here.
Keywords: pulmonary hypertension; treatment; promising drug; tetramethylpyrazine promising ... See more keywords
Mdivi-1: a promising drug and its underlying mechanisms in the treatment of neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-443
Abstract: Mitochondria are energy-producing organelles, and neurons are high energy consumption cells. Therefore, mitochondrial dysfunction is a critical factor in neurodegenerative processes. Mitochondrial division inhibitor-1 (Mdivi-1) is a small chemical inhibitor of mitochondrial division dynamin, which… read more here.
Keywords: mechanisms treatment; drug underlying; mdivi promising; underlying mechanisms ... See more keywords
Albumin-based Nanoparticles as Promising Drug Delivery Systems for Cancer Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Current Pharmaceutical Analysis"
DOI: 10.2174/1573412916999200421142008
Abstract: Albumin is an ideal material for the production of drug carrier nanoparticular systems since it is a versatile and functional protein that has been proven to be biodegradable and biocompatible, non-toxic, and immunogenic. Albumin nanoparticles… read more here.
Keywords: nanoparticles promising; albumin nanoparticles; based nanoparticles; promising drug ... See more keywords
Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.680633
Abstract: Epigenetic dysregulation has been implicated in a variety of pathological processes including carcinogenesis. A major group of enzymes that influence epigenetic modifications are lysine demethylases (KDMs) also known as “erasers” which remove methyl groups on… read more here.
Keywords: drug targets; melanoma cancers; demethylases promising; lysine demethylases ... See more keywords
Epigallocatechin-3-gallate: A phytochemical as a promising drug candidate for the treatment of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.977521
Abstract: Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from green tea extract, possesses versatile bioactivities that can combat many diseases. During the last decade, EGCG was shown to be effective in experimental models of Parkinson’s… read more here.
Keywords: phytochemical promising; epigallocatechin gallate; parkinson disease; gallate phytochemical ... See more keywords
DR2 blocker thioridazine: A promising drug for ovarian cancer therapy
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DOI: 10.3892/ol.2020.12081
Abstract: [This corrects the article DOI: 10.3892/ol.2017.7184.]. read more here.
Keywords: thioridazine promising; dr2 blocker; promising drug; blocker thioridazine ... See more keywords
Metformin: A promising drug for human cancers
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DOI: 10.3892/ol.2022.13325
Abstract: Small-molecule chemical drugs are of great significance for tumor-targeted and individualized therapies. However, the development of new small-molecule drugs, from basic experimental research and clinical trials to final application in clinical practice, is a long… read more here.
Keywords: drug human; tumor; metformin promising; human cancers ... See more keywords
Paxlovid: A promising drug for the challenging treatment of SARS-COV-2 in the pandemic era
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Pharmacology"
DOI: 10.4103/ijp.ijp_291_22
Abstract: Coronavirus infection is a pandemic threat and the most dangerous disease of the 21st century. Despite the rigorous exertion of world-class researchers, there is no perfect cure for it. It has been seen in presently… read more here.
Keywords: paxlovid promising; drug challenging; treatment; drug ... See more keywords