Articles with "promising modulators" as a keyword



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Pyxinol bearing amino acid residues: Easily achievable and promising modulators of P-glycoprotein-mediated multidrug resistance.

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Published in 2021 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2021.113317

Abstract: The P-glycoprotein (Pgp) is a major transporter involved in multidrug resistance (MDR) of cancer cells leading to chemotherapy failure. In our previous study, we demonstrated that the amide derivatives of pyxinol are promising modulators against… read more here.

Keywords: amino acid; promising modulators; pyxinol; resistance ... See more keywords