Maleimide structure: a promising scaffold for the development of antimicrobial agents.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.1877675
Abstract: Natural compounds bearing maleimide rings are a series of secondary metabolites derived from fungi/marine microorganisms, which are characterized by a general structure -CO-N(R)-CO-, and the R group is normally substituted with alkyl or aryl groups.… read more here.
Keywords: antimicrobial agents; promising scaffold; structure promising; maleimide structure ... See more keywords
Benzothiazole as a Promising Scaffold for the Development of Antifungal Agents.
Sign Up to like & getrecommendations! Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026623666230124152429
Abstract: Despite great efforts in the discovery of antifungal drugs in the last two decades, the increasing incidence of infectious diseases from diverse pathogenic fungi threatens public healthcare and medical sector. Particularly, the invasive infection caused… read more here.
Keywords: benzothiazole promising; development; antifungal drugs; activity ... See more keywords
1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.874709
Abstract: The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies. In a previous work, we found that several 1,4-dihydropyridine (DHP)-based antihypertensive drugs exhibited strong bactericidal… read more here.
Keywords: antimicrobials helicobacter; scaffold novel; promising scaffold; dihydropyridine promising ... See more keywords
The Triprenylated Anthranoid Ferruginin A, a Promising Scaffold for the Development of Novel Antibiotics against Gram-Positive Bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11010084
Abstract: In today’s post-antibiotic era, the search for new antimicrobial compounds is of major importance and nature represents one of the primary sources of bioactive molecules. In this work, through a cheminformatics approach, we clustered an… read more here.
Keywords: anthranoid ferruginin; scaffold development; ferruginin; positive bacteria ... See more keywords