Mannich Bases: Promising Scaffolds for the Treatment of Infectious Diseases.
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DOI: 10.2174/0109298673360057250219044138
Abstract: Mannich bases, synthesized through the reaction of an aldehyde, a primary or secondary amine, and a compound bearing an acidic hydrogen atom, represent a versatile class of scaffolds in medicinal chemistry. This review explores their… read more here.
Keywords: scaffolds treatment; chemistry; bases promising; infectious diseases ... See more keywords
Cyclic Peptides: Promising Scaffolds for Biopharmaceuticals
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DOI: 10.3390/genes9110557
Abstract: To date, small molecules and macromolecules, including antibodies, have been the most pursued substances in drug screening and development efforts. Despite numerous favorable features as a drug, these molecules still have limitations and are not… read more here.
Keywords: promising scaffolds; drug; scaffolds biopharmaceuticals; peptides promising ... See more keywords