Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02101-2
Abstract: The role of glutaminolysis in providing metabolites to support tumour growth is well-established, but the involvement of glutamine metabolism in invasive processes is yet to be elucidated. Here we show that normal mammary epithelial cells… read more here.
Keywords: promote invasiveness; glutamate; breast cancer; cancer cells ... See more keywords
Exosomes secreted from mesenchymal NSCLC cells to promote invasiveness and metastatic capability of recipient cells through UCHL1.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24008
Abstract: e24008Background: Cancer-derived exosomes are intracellular signaling organelles that can act to help cancer cells invade neighboring tissues, induce epithelial-mesenchymal transition (EMT) in targ... read more here.
Keywords: secreted mesenchymal; promote invasiveness; cells promote; nsclc cells ... See more keywords