Extracellular vesicle packaged LMP1-activated fibroblasts promote tumor progression via autophagy and stroma-tumor metabolism coupling.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.03.004
Abstract: Several reports have demonstrated that Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1), which is transferred by extracellular vesicles (EVs) or exosomes, can promote cancer progression. However, its mechanism is still not fully understood. In… read more here.
Keywords: tumor progression; packaged lmp1; lmp1 activated; promote tumor ... See more keywords
IL-35 induces N2 phenotype of neutrophils to promote tumor growth
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16819
Abstract: IL-35 is an immunosuppressive cytokine and exerts regulatory effects on T cells, B cells, macrophages and dendritic cells. Neutrophils are important innate immune cells that play key roles in tumor development. The effect of IL-35… read more here.
Keywords: neutrophils promote; induces phenotype; phenotype neutrophils; promote tumor ... See more keywords
CD36 and Its Role in Regulating the Tumor Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology"
DOI: 10.3390/curroncol29110642
Abstract: CD36 is a transmembrane glycoprotein that binds to a wide range of ligands, including fatty acids (FAs), cholesterol, thrombospondin-1 (TSP-1) and thrombospondin-2 (TSP-2), and plays an important role in lipid metabolism, immune response, and angiogenesis.… read more here.
Keywords: cd36; role; promote tumor; angiogenesis ... See more keywords