Modular Divergent Synthesis of Functionalized Indoles via TFA-Promoted Amino-Claisen Rearrangement at Room Temperature.
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DOI: 10.1021/acs.orglett.3c00764
Abstract: A conceptually novel approach for the modular and divergent synthesis of highly functionalized indoles via trifluoroacetic acid-promoted amino-Claisen rearrangement is reported. This metal-free protocol could be performed at room temperature with wide functional group tolerance.… read more here.
Keywords: amino claisen; functionalized indoles; divergent synthesis; indoles via ... See more keywords