Lewis acid-promoted cascade reaction for the synthesis of Michael acceptors and its application in a dimerization reaction
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.05.017
Abstract: Abstract An efficient Lewis acid-promoted cascade reaction with dimethyl sulfoxide as a methylene source for the synthesis of Michael acceptors is reported. The key to developing this procedure is the selection of a mild base… read more here.
Keywords: michael; lewis acid; cascade reaction; promoted cascade ... See more keywords
Synthesis of 3H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate.
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DOI: 10.1021/acs.orglett.1c00568
Abstract: A nickel-promoted cascade annulation reaction for the facile synthesis of 3H-1,2,4-triazol-3-ones from readily available hydrazonoyl chlorides and sodium cyanate has been developed. The transformation occurs through a cascade nickel-promoted intermolecular nucleophilic addition-elimination process, intramolecular nucleophilic… read more here.
Keywords: hydrazonoyl chlorides; chlorides sodium; promoted cascade; triazol ones ... See more keywords
Synthesis of the Indolizidine Core of Virosinine A via a Microwave-Promoted Cascade Cyclization Involving Iminyl Radicals.
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DOI: 10.1021/acs.orglett.3c03852
Abstract: The indolizidine core of virosinine A was synthesized by means of a microwave-promoted cascade reaction featuring 5-exo-trig iminyl radical cyclization, thiyl radical elimination, and intramolecular imine alkylation. The resulting bicyclic iminium ion underwent stereoselective reduction… read more here.
Keywords: cyclization; promoted cascade; indolizidine core; core virosinine ... See more keywords
dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides access to C2-spiro-pseudoindoxyls
Sign Up to like & getrecommendations! Published in 2024 at "Organic Chemistry Frontiers"
DOI: 10.1039/d4qo00016a
Abstract: A dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides access to C2-spiro-pseudoindoxyls under mild conditions has been developed. The desired products were obtained in high to excellent yields. A mechanism... read more here.
Keywords: reaction nitrophenylpropiolamides; dppb tfoh; nitrophenylpropiolamides access; tfoh promoted ... See more keywords