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Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.12.011
Abstract: Abstract A K 3 PO 4 promoted dipolar [3+3] cyclization of dihydroisoquinoline imines and arylacyl bromides has been developed. This process realized the direct synthesis of pyrazino[2,1- a ]isoquinoline derivatives in 44–69% yields. A head…
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Keywords:
dipolar cyclization;
direct synthesis;
synthesis pyrazino;
isoquinoline derivatives ... See more keywords