Novel synthesis of perfluoroalkylated indolizinylphosphonates via a DIPEA-promoted one-pot process
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DOI: 10.1016/j.tet.2017.11.050
Abstract: Abstract DIPEA-promoted one-pot synthesis of perfluoroalkylated indolizinylphosphonates by the reaction of pyridines 1, bromomethyl ketones 2 with perfluoroalkynylphosphonates 3 is described. This procedure is compatible with a broad range of functional groups in both pyridines… read more here.
Keywords: perfluoroalkylated indolizinylphosphonates; dipea promoted; one pot; promoted one ... See more keywords
Iodine-promoted one-pot synthesis of 1,3,4-oxadiazole scaffolds via sp3 C–H functionalization of azaarenes
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DOI: 10.1039/c9nj03573g
Abstract: An efficient metal-free one-pot protocol has been developed for the construction of 1,3,4-oxadiazole derivatives via iodine-mediated oxidative amination of benzylic C–H bonds of azaarenes. read more here.
Keywords: pot; iodine promoted; pot synthesis; synthesis oxadiazole ... See more keywords
Polyphosphoric acid-promoted one-pot synthesis and neuroprotective effects of flavanones against NMDA-induced injury in PC12 cells
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DOI: 10.1039/d2ra03562f
Abstract: We report herein an efficient polyphosphoric acid (PPA) promoted one-pot protocol for the synthesis of flavanone derivatives from 2-hydroxyacetophenones and benzaldehydes. A variety of flavanones were produced in moderate to excellent yields and evaluated for… read more here.
Keywords: polyphosphoric acid; neuroprotective effects; nmda induced; one pot ... See more keywords
An iodine-promoted one-pot and metal-free access to indolin-2-ones
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DOI: 10.1177/1747519819875862
Abstract: A new method for the synthesis of indolin-2-ones has been realized by an I2-promoted oxidative reaction from 1,2,3,3-tetramethyl-3H-indolium iodides. This transformation proceeded smoothly under metal-free and peroxide-free conditions in a cascade manner. read more here.
Keywords: indolin ones; iodine promoted; promoted one; one pot ... See more keywords
DABCO- and DBU-promoted one-pot reaction of N-sulfonyl ketimines with Morita–Baylis–Hillman carbonates: a sequential approach to (2-hydroxyaryl)nicotinate derivatives
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DOI: 10.3762/bjoc.14.254
Abstract: An intriguing DABCO-catalyzed and DBU-promoted one-pot synthesis of an important class of (2-hydroxyaryl)pyridine derivatives bearing a carboxylate or a nitrile group suitably placed at C3 position of the aza-ring has been achieved in acceptable chemical… read more here.
Keywords: hydroxyaryl; one pot; promoted one; dbu promoted ... See more keywords