FeCl3-Promoted ring size-dictating diversity-oriented synthesis (DOS) of N-heterocycles using in situ-generated cyclic imines and enamines.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc03375k
Abstract: The FeCl3-promoted ring size-controlled oxidative activation of o-alkynylanilines opens up a complementary appealing protocol for poly-N-heterocycle synthesis. When electron-poor π-alkyne iron species combine with cyclic enamines obtained from cyclohexanone and β-tetralone, they undergo a regioselective… read more here.
Keywords: size dictating; ring size; promoted ring; fecl3 promoted ... See more keywords
Formation of β-cyano-ketones through cyanide-promoted ring-opening of cyclic organic carbonates
Sign Up to like & getrecommendations! Published in 2021 at "Organic Chemistry Frontiers"
DOI: 10.1039/d1qo00770j
Abstract: In an unusual cascade process involving KCN, vinyl cyclic carbonates are converted into β-cyano ketones with the subsequent extrusion of carbon dioxide and acetonitrile facilitating a Michael addition to an intermediate α,β-unsaturated ketone. read more here.
Keywords: cyano ketones; ketones cyanide; formation cyano; promoted ring ... See more keywords