Ultrasound promoted synthesis, characterization and computational studies of some thiourea derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128302
Abstract: Abstract Synthesis of some thiourea derivatives have been achieved by using ultrasound, the compounds have been characterised using IR, NMR, GC-MS and elemental analysis. The single crystal X-ray structure of N-[(benzyloxy)methanethioyl]benzamide (IV), 1-benzoyl-3-(2-hydroxyethyl)thiourea (V) and… read more here.
Keywords: ultrasound promoted; promoted synthesis; characterization computational; thiourea derivatives ... See more keywords
Visible-light promoted synthesis of 3-arylthioindoles from indoles and diaryl disulfides
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.05.090
Abstract: Abstract 3-Arylthioindoles could be synthesized in good yields via the photoirradiation of indoles and disulfides. The reaction is efficiently promoted by the catalytic amount of sodium iodide. A reaction mechanism involving the electrophilic substitution of… read more here.
Keywords: indoles diaryl; visible light; arylthioindoles indoles; promoted synthesis ... See more keywords
Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.02.011
Abstract: Abstract The versatile conversion of propargylic amides to the respective 2-substituted 5-methyloxazoles was efficiently catalyzed by Zn(OTf)2 (5 mol%) under microwave irradiation in toluene. The method was applicable to a wide range of aliphatic, aromatic and… read more here.
Keywords: catalyzed microwave; substituted methyloxazoles; otf catalyzed; propargylic amides ... See more keywords
A Mild Silica Gel Promoted Synthesis and Initial Functional Study of Tetrapyridyl Tetrahydropyrrolopyrrolones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02095
Abstract: A one-pot strategy with yields up to 82% was reported to generate 2-(pyridin-2-yl)-2-(3,3a,6-tris(5-pyridin-2-yl)-5-oxohexahydropyrrolo[3,2-b] pyrrol-2(1H)-ylidene)acetonitrile 1a and its derivatives 1b-d. Silica gel promoted quantitative conversion from stable intermediate to 1a within 30 min at room temperature.… read more here.
Keywords: mild silica; initial functional; gel promoted; synthesis initial ... See more keywords
Base-Promoted Synthesis of Quinoline-4(1H)-thiones from o-Alkynylanilines and Aroyl Isothiocyanates.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02993
Abstract: A base-promoted synthesis of quinoline-4(1H)-thiones has been accomplished from the in situ generated o-alkynylthiourea, obtained by reacting o-alkynylanilines with aroyl/acyl isothiocyanates. A 6-exo-dig S-cyclization of the in situ generated thiourea is followed by a rearrangement… read more here.
Keywords: promoted synthesis; synthesis quinoline; quinoline; alkynylanilines aroyl ... See more keywords
TfOH-promoted synthesis of indoles and benzofurans involving cyclative transposition of vinyl ketone.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03730k
Abstract: A metal-free approach to construct indole rings from vinylogous amides derived from o-alkynylanilines involving a cyclization, retro-aza-Michael reaction and amine trapping cascade is reported here. This atom-economical transformation has been extended to synthesize benzofuran derivatives… read more here.
Keywords: benzofurans involving; involving cyclative; indoles benzofurans; synthesis indoles ... See more keywords