Molecular cloning and characterization of Cinnamoyl‐CoA reductase promoter gene from Asarum sieboldii Miq
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DOI: 10.1002/bab.2330
Abstract: Asarum sieboldii Miq., a perennial herb of the family Aristolochiaceae, is widely used in China to treat cold, fever, aphthous stomatitis, toothache, gingivitis, and rheumatoid arthritis. Methyleugenol is the most representative pharmacological constituent of this… read more here.
Keywords: promoter; coa reductase; asarum sieboldii; cinnamoyl coa ... See more keywords
A Strong Hybrid Fatty Acid Inducible Transcriptional Sensor Built From Yarrowia lipolytica Upstream Activating and Regulatory Sequences
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DOI: 10.1002/biot.201700248
Abstract: The engineering of Yarrowia lipolytica to accumulate lipids with high titers and productivities has been enabled with a handful of constitutive promoters for pathway engineering. However, the development of promoters that are both strong and… read more here.
Keywords: hybrid fatty; fatty acid; strong hybrid; acid inducible ... See more keywords
Characterization of essential elements for improved episomal expressions in Kluyveromyces marxianus
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DOI: 10.1002/biot.202100382
Abstract: Kluyveromyces marxianus is a promising cell factory for producing heterologous proteins. Essential components including partition element, copy number control element, promoter, and terminator in multicopy plasmids applicable for K. marxianus are not extensively characterized. The… read more here.
Keywords: promoter; kluyveromyces marxianus; pkd1 based; based plasmid ... See more keywords
In situ enhancement of surfactin biosynthesis in Bacillus subtilis using novel artificial inducible promoters
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DOI: 10.1002/bit.26197
Abstract: Surfactin‐family lipopeptides are green biosurfactants with substantial industrial potential. The major problem prohibiting surfactin use is the low titer of the wild producer, Bacillus subtilis. Using transcriptomic analysis, four strong promoters, PgroE, Pcdd, PrplK, and… read more here.
Keywords: inducible promoters; surfactin; promoter; bacillus subtilis ... See more keywords
Integration of metabolic pathway manipulation and promoter engineering for the fine‐tuned biosynthesis of malic acid in Bacillus coagulans
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DOI: 10.1002/bit.27780
Abstract: Bacillus coagulans, a thermophilic facultative anaerobe, is a favorable chassis strain for the biosynthesis of desired products. In this study, B. coagulans was converted into an efficient malic acid producer by metabolic engineering and promoter… read more here.
Keywords: malic acid; biosynthesis malic; promoter engineering; promoter ... See more keywords
Radiomic study on preoperative multi‐modal magnetic resonance images identifies IDH‐mutant TERT promoter‐mutant gliomas
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DOI: 10.1002/cam4.5097
Abstract: Gliomas with comutations of isocitrate dehydrogenase (IDH) genes and telomerase reverse transcriptase (TERT) gene promoter (IDHmut pTERTmut) show distinct biological features and respond to first‐line treatment differently in comparison with other gliomas. This study aimed… read more here.
Keywords: promoter; study preoperative; gliomas; preoperative multi ... See more keywords
Repressor‐Like On‐Off Regulation of Protein Expression by the DNA‐Binding Transcription Activator‐Like Effector in T7 Promoter‐Based Cell‐Free Protein Synthesis
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DOI: 10.1002/cbic.202000591
Abstract: The aim of this study was to develop a transcription activator‐like effector (TALE)‐based technology to regulate protein synthesis in cell‐free systems. We attempted to regulate the T7 promoter system, which has no natural mechanism of… read more here.
Keywords: protein; tale; expression; protein synthesis ... See more keywords
Morphology Evolution of Hcp Cobalt Nanoparticles Induced by Ru Promoter
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DOI: 10.1002/cctc.201902270
Abstract: The modification of the equilibrium morphology to expose active facets of cobalt nanoparticles is essential for tailoring and controlling its catalytic performance. Periodic density functional theory (DFT) was applied to systematically investigate the structure and… read more here.
Keywords: nanoparticles induced; induced promoter; morphology; cobalt nanoparticles ... See more keywords
Quantitative characterization of human oncogene promoter G‐quadruplex DNA‐ligand interactions using a combination of mass spectrometry and capillary electrophoresis
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DOI: 10.1002/elps.202100077
Abstract: Human c‐KIT oncogene is known to regulate cell growth and proliferation, and thus, acts as a probable target in the treatment of gastrointestinal tumors (GIST). To identify small molecule ligands which can specifically bind with… read more here.
Keywords: capillary electrophoresis; combination; oncogene; mass spectrometry ... See more keywords
Transcriptional repression and apoptosis influence the effect of APOBEC3A/3B functional polymorphisms on biliary tract cancer risk
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DOI: 10.1002/ijc.33930
Abstract: APOBEC3‐related somatic mutations are predominant in biliary tract cancers (BTCs). We aimed to elucidate the roles of APOBEC3A/3B functional polymorphisms and their influencing factors on the development of cholangiocarcinoma (CCA) and gallbladder cancer (GBC). Polymorphisms… read more here.
Keywords: promoter; apoptosis; risk; activity ... See more keywords
A putative association of interleukin‐10 promoter polymorphisms with cardiovascular disease
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DOI: 10.1002/iub.1637
Abstract: Interleukin‐10 (IL‐10) is an anti inflammatory cytokine involved in the ongoing coronary inflammation and related patho‐physiological processes. The piece of work presented herein is aimed at investigating possible association of polymorphisms in IL‐10 promoter with… read more here.
Keywords: cvd patients; cvd; association; promoter ... See more keywords