Exact distributions for stochastic gene expression models with arbitrary promoter architecture and translational bursting.
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DOI: 10.1103/physreve.105.014405
Abstract: Gene expression in individual cells is inherently variable and sporadic, leading to cell-to-cell variability in mRNA and protein levels. Recent single-cell and single-molecule experiments indicate that promoter architecture and translational bursting play significant roles in… read more here.
Keywords: stochastic gene; promoter architecture; gene expression; expression ... See more keywords
Promoter Architecture Differences among Alphaproteobacteria and Other Bacterial Taxa
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DOI: 10.1128/msystems.00526-21
Abstract: Transcription of DNA to RNA by RNA polymerase is essential for cells to grow, develop, and respond to stress. Understanding the process and control of transcription is important for health, disease, the environment, and biotechnology.… read more here.
Keywords: dna; transcription; promoter; dependent promoters ... See more keywords
Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae
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DOI: 10.3390/metabo10080320
Abstract: Promoters play an essential role in the regulation of gene expression for fine-tuning genetic circuits and metabolic pathways in Saccharomyces cerevisiae (S. cerevisiae). However, native promoters in S. cerevisiae have several limitations which hinder their… read more here.
Keywords: engineering; promoter engineering; saccharomyces cerevisiae; architecture promoter ... See more keywords