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Published in 2018 at "Biotechnology Journal"
DOI: 10.1002/biot.201700380
Abstract: Glyco‐modulation of therapeutic proteins produced in plants has shown great success. Plant‐based expression platforms for tailored human‐like N‐glycosylation are based on the overexpression of foreign genes. However, drawbacks such as protein miss targeting, interference with…
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Keywords:
efficiency;
promoter choice;
engineering;
plant ... See more keywords
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Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108048
Abstract: During thymic development and upon peripheral activation, T cells undergo extensive phenotypic and functional changes coordinated by lineage-specific developmental programs. To characterize the regulatory landscape controlling T cell identity, we perform a wide epigenomic and transcriptional analysis…
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Keywords:
enhancer usage;
cell;
promoter choice;
enhancer ... See more keywords