Integration of metabolic pathway manipulation and promoter engineering for the fine‐tuned biosynthesis of malic acid in Bacillus coagulans
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27780
Abstract: Bacillus coagulans, a thermophilic facultative anaerobe, is a favorable chassis strain for the biosynthesis of desired products. In this study, B. coagulans was converted into an efficient malic acid producer by metabolic engineering and promoter… read more here.
Keywords: malic acid; biosynthesis malic; promoter engineering; promoter ... See more keywords
Activation and Characterization of Lanthomicins A–C by Promoter Engineering in Streptomyces chattanoogensis L10
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.902990
Abstract: The emergence of drug resistance highlights the importance of new drug discovery. Microbial secondary metabolites encoded in biosynthetic gene clusters (BGCs) are a prolific source of drugs, whereas most of these BGCs are cryptic. Thus,… read more here.
Keywords: drug discovery; drug; promoter engineering;
Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2020 at "Metabolites"
DOI: 10.3390/metabo10080320
Abstract: Promoters play an essential role in the regulation of gene expression for fine-tuning genetic circuits and metabolic pathways in Saccharomyces cerevisiae (S. cerevisiae). However, native promoters in S. cerevisiae have several limitations which hinder their… read more here.
Keywords: engineering; promoter engineering; saccharomyces cerevisiae; architecture promoter ... See more keywords