MucR binds multiple target sites in the promoter of its own gene and is a heat‐stable protein: Is MucR a H‐NS‐like protein?
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DOI: 10.1002/2211-5463.12411
Abstract: The protein MucR from Brucella spp. is involved in the expression regulation of genes necessary for host interaction and infection. MucR is a member of the Ros/MucR family, which comprises prokaryotic zinc‐finger proteins and includes… read more here.
Keywords: protein; protein mucr; target; gene ... See more keywords
Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia
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DOI: 10.1038/s41598-021-88000-5
Abstract: Chronic hypoxia is a major contributor to Chronic Kidney Disease (CKD) after Acute Kidney Injury (AKI). However, the temporal relation between the acute insult and maladaptive renal response to hypoxia remains unclear. In this study,… read more here.
Keywords: binding site; hif1 binding; hif1; vegfa ... See more keywords
MGMT promoter gene methylation and neurological scale improvement in glioma: a cohort study
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DOI: 10.12688/f1000research.51213.1
Abstract: Background : Glioma is one of the most common primary brain tumours and conveys a dismal prognosis despite aggressive treatment. Several biomarkers have been studied in the hope of yielding better diagnostic accuracy and improving patient management. Besides survival, functional and neurological disability are concerns that have no lesser importance. In 2017, a disease-specific assessment… read more here.
Keywords: gene methylation; mgmt promoter; improvement; promoter gene ... See more keywords
DNA co-methylation analysis of lincRNAs across nine cancer types reveals novel potential epigenetic biomarkers in cancer.
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DOI: 10.2217/epi-2018-0138
Abstract: Aim: The potential functions and prognostic value of lincRNAs with co-methylation events are explored in 9 cancer types. Materials & methods: Here, we evaluated the co-methylation events in promoter and gene-body regions between two lincRNAs… read more here.
Keywords: cancer types; methylation; lincrnas across; methylation events ... See more keywords
Functional Characterization of the CpNAC1 Promoter and Gene from Chimonanthus praecox in Arabidopsis
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DOI: 10.3390/ijms24010542
Abstract: The NAC (NAM, ATAF, and CUC) gene family is one of the largest plant-specific transcription factor families. Its members have various biological functions that play important roles in regulating plant growth and development and in… read more here.
Keywords: promoter gene; cpnac1; abiotic stresses; cpnac1 promoter ... See more keywords