IL10 promoter haplotypes may contribute to altered cytokine expression and systemic inflammation in celiac disease.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.02.010
Abstract: Celiac disease (CD) is an autoimmune/inflammatory condition triggered by dietary gluten intake in genetically predisposed individuals. Though associations with MHC class II HLA-DQ2 or -DQ8 are the primary and necessary genetic predisposition for CD, >97%… read more here.
Keywords: promoter haplotypes; il10 promoter; celiac disease; expression ... See more keywords
The analysis of GSTA1 promoter genetic and functional diversity of human populations
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-83996-2
Abstract: GSTA1 encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTA1 has several functional SNPs within… read more here.
Keywords: human populations; gsta1 promoter; analysis; promoter haplotypes ... See more keywords