Risk SNP-Mediated Enhancer–Promoter Interaction Drives Colorectal Cancer through Both FADS2 and AP002754.2
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DOI: 10.1158/0008-5472.can-19-2389
Abstract: This study provides an oncogenic regulatory circuit among several oncogenes including E2F1, FADS2, and AP002754.2 underlying the association of rs174575 with the colorectal cancer risk, which is driven by long-range enhancer-promoter interaction loops. Although genome-wide… read more here.
Keywords: fads2; cancer; risk; enhancer promoter ... See more keywords