Transcriptomic analysis on the promoter regions discover gene networks involving mastitis in cattle.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2019.103801
Abstract: Mastitis is one of the costliest diseases in dairy farms caused by infection of different microorganisms such as Escherichia coli, Streptococcus uberis and Staphylococcus aureus. Promoters are significantly involved in regulating gene expression and shedding… read more here.
Keywords: mastitis; gene networks; analysis; promoter regions ... See more keywords
Identification of putative promoters in 48 eukaryotic genomes on the basis of DNA free energy
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22129-8
Abstract: Transcription is an intricate mechanism and is orchestrated at the promoter region. The cognate motifs in the promoters are observed in only a subset of total genes across different domains of life. Hence, sequence-motif based… read more here.
Keywords: promoter; dna; identification putative; promoter regions ... See more keywords
Transcriptional activities of two newly identified Haemaphysalis longicornis tick‐derived promoter regions in the Ixodes scapularis tick cell line (ISE6)
Sign Up to like & getrecommendations! Published in 2018 at "Insect Molecular Biology"
DOI: 10.1111/imb.12497
Abstract: Ticks are obligate haematophagous ectoparasites considered to be second to mosquitoes as vectors of human diseases and the most important vector for animals. Despite efforts to control tick infestations, they remain a serious health problem.… read more here.
Keywords: vector; cell line; tick; tick cell ... See more keywords
Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NFκB-mediated inflammation in IUGR mice
Sign Up to like & getrecommendations! Published in 2020 at "Biology Open"
DOI: 10.1242/bio.049106
Abstract: ABSTRACT Infants with intrauterine growth retardation (IUGR) have a high risk of developing bronchial asthma in childhood, but the underlying mechanisms remain unclear. This study aimed to disclose the role of vascular non-inflammatory molecule 1… read more here.
Keywords: iugr asthmatic; asthmatic mice; promoter regions; mice ... See more keywords
Hypermethylated DNA, a circulating biomarker for colorectal cancer detection
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0180809
Abstract: Background Colorectal cancer (CRC) is one of the most common cancers in the western world. Screening is an efficient method of reducing cancer-related mortality. Molecular biomarkers for cancer in general and CRC in particular have… read more here.
Keywords: hypermethylated dna; detection; promoter regions; crc ... See more keywords
A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the HNF1B gene.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine journal"
DOI: 10.1507/endocrj.ej20-0038
Abstract: Pancreatic tail hypoplasia is a common manifestation of maturity onset diabetes of the young (MODY) 5 that can cause reno-genito-urinary malformations such as renal cysts and bicornuate uterus. A 69-year-old female was admitted to our… read more here.
Keywords: minimal promoter; coding minimal; promoter regions; regions hnf1b ... See more keywords
Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s374951
Abstract: Background In most cell types, replicative senescence (RS) is supposed to be a principle causative factor for aging. Atrial fibrosis, pathologically characterized by proliferation of atrial fibroblasts (AFs) and excessive accumulation of extracellular matrix proteins,… read more here.
Keywords: ezh2 inhibits; promoter regions; replicative senescence; atrial fibroblasts ... See more keywords
Abnormal Hypermethylation of CpG Dinucleotides in Promoter Regions of Matrix Metalloproteinases Genes in Breast Cancer and its Relation to Epigenomic Subtypes and HER2 Overexpression
Sign Up to like & getrecommendations! Published in 2020 at "Biomedicines"
DOI: 10.3390/biomedicines8050116
Abstract: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) substantially contribute to the regulation of intercellular interactions and thereby play a role in maintaining the tissue structure and function. We examined methylation of a subset of… read more here.
Keywords: promoter regions; abnormal hypermethylation; cpg; breast cancer ... See more keywords