ARF6 Promotes AML Progression via Activation of PI3K/AKT/mTOR Signaling
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DOI: 10.1002/cam4.70872
Abstract: Acute myeloid leukemia (AML) represents a highly aggressive hematological malignancy characterized by a poor prognosis and a pressing demand for innovative diagnostic and prognostic biomarkers. Recent studies have indicated that ADP‐ribosylation factor 6 (ARF6) is… read more here.
Keywords: promotes aml; via activation; activation pi3k; arf6 promotes ... See more keywords
Abstract 5851: Dysregulated RNA splicing promotes AML quiescence and chemoresistance
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DOI: 10.1158/1538-7445.am2024-5851
Abstract: Chemotherapy is the first-line treatment for patients with acute myeloid leukemia (AML). Although most achieve initial remission, an estimated 50% of patients will relapse with poor clinical outcome. The paucity of genetic lesions in AML… read more here.
Keywords: promotes aml; rna splicing; dysregulated rna; splicing promotes ... See more keywords