MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21167
Abstract: We investigated the mechanisms by which microRNA (miR)-182 promotes apoptosis and inhibits proliferation in human osteosarcoma (OS) cells. Levels of miR-182 and Homeobox A9 (HOXA9) expression were compared between human OS and normal cells. Subjects… read more here.
Keywords: promotes apoptosis; mir 182; hoxa9; proliferation ... See more keywords
CYLD Promotes Apoptosis of Nasopharyngeal Carcinoma Cells by Regulating NDRG1
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DOI: 10.2147/cmar.s268216
Abstract: Purpose Nasopharyngeal carcinoma (NPC) is among the most common malignancies derived from the epithelium of the nasopharynx. To date, the regulatory networks involved in NPC have not been fully identified. Previous studies revealed multiple loss-of-function… read more here.
Keywords: cyld; cyld promotes; promotes apoptosis; apoptosis nasopharyngeal ... See more keywords
lncRNA LINC00960 promotes apoptosis by sponging ubiquitin ligase Nrdp1-targeting miR-183-5p
Sign Up to like & getrecommendations! Published in 2023 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2023005
Abstract: The ubiquitin ligase Nrdp1/RNF41 promotes the ubiquitin-dependent degradation of multiple important substrates, including BRUCE/BIRC6, a giant ubiquitin-conjugating enzyme inhibiting both apoptosis and autophagy. miR-183-5p is associated with various malignancies potentially by targeting dozens of genes.… read more here.
Keywords: lncrna linc00960; nrdp1 targeting; mir 183; ubiquitin ligase ... See more keywords