Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5251
Abstract: PRDM5 is considered a tumor suppressor in several types of solid tumors and is involved in multiple cellular processes. However, target genes regulated by PRDM5 in lung cancer and its potential mechanism are poorly defined. read more here.
Keywords: prdm5; cell proliferation; prdm5 promotes; promotes cell ... See more keywords
Hepatitis B Virus–Upregulated LNC‐HUR1 Promotes Cell Proliferation and Tumorigenesis by Blocking p53 Activity
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30098
Abstract: Recent studies have indicated that a number of long noncoding RNAs (lncRNAs) are dysregulated in hepatocellular carcinoma, while their aberrant expressions are associated with tumorigenesis and poor prognosis. To identify hepatitis B virus (HBV)‐related lncRNAs,… read more here.
Keywords: tumorigenesis; hur1 promotes; cell proliferation; lnc hur1 ... See more keywords
Acetate Promotes T Cell Effector Function during Glucose Restriction.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.04.022
Abstract: Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell function. For instance, cancer cells use… read more here.
Keywords: function glucose; effector function; promotes cell; function ... See more keywords
CMTM3 overexpression promotes cell apoptosis while DHT promotes cell proliferation in hair follicle stem cells (HFSCs).
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.12.029
Abstract: In Yangtze River Delta white goat, hypermethylation of CMTM3 leads to a decreased expression level in high quality brush hair. However, the regulation of CMTM3 expression and its function in hair follicle stem cells (HFSCs)… read more here.
Keywords: hair follicle; follicle stem; proliferation; cmtm3 ... See more keywords
THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2318773121
Abstract: Significance Therapies based on immune checkpoint blockades have revolutionized the field of cancer immunotherapy, yet the molecular mechanism underlying the signaling activity of these receptors remains ill-defined. Here, we show that the T cell lineage… read more here.
Keywords: themis promotes; cell development; promotes cell; btla ... See more keywords
MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/2381482
Abstract: Emerging evidence shows that microRNAs (miRNAs) play important roles in the regulation of various biological and pathologic processes in human cancers and the aberrant expression of miRNAs contributes to the tumor development. In this study,… read more here.
Keywords: cell viability; pancreatic cancer; metastasis; mir 451 ... See more keywords
Retracted: LINC00518 Promotes Cell Malignant Behaviors via Influencing EIF4A3-Mediated mRNA Stability of MITF in Melanoma
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DOI: 10.1155/2024/9846817
Abstract: [This retracts the article DOI: 10.1155/2022/3546795.]. read more here.
Keywords: behaviors via; linc00518 promotes; retracted linc00518; cell malignant ... See more keywords
USP26 Promotes Cell Proliferation of Gastric Cancer by Stabilizing c-Myc.
Sign Up to like & getrecommendations! Published in 2025 at "DNA and cell biology"
DOI: 10.1177/10445498251389596
Abstract: Gastric cancer is one of the leading causes of cancer mortality worldwide, but the underlying molecular mechanisms by which gastric cancer progresses are not fully understood. While deubiquitinases have emerged as promising therapeutic targets in… read more here.
Keywords: cancer; usp26 promotes; cell proliferation; gastric cancer ... See more keywords
EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202051679
Abstract: The endoplasmic reticulum (ER) is a subcellular organelle crucial for protein folding and calcium storage. Accumulation of unfolded proteins or calcium depletion causes ER stress. Deficiency of ER stress adaptation leads to apoptosis, which is… read more here.
Keywords: stress; calcium; ei24; ei24 promotes ... See more keywords
FOXK1, Regulated by miR-365-3p, Promotes Cell Growth and EMT Indicates Unfavorable Prognosis in Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s212702
Abstract: Background Forkhead box K1 (FOXK1) is members of the FOX transcription factor family. Previous work has found out that FOXK1 promotes cell proliferation, migration and invasion in several cancers, such as gastric cancer, glioma cancer… read more here.
Keywords: foxk1; mir 365; cancer; promotes cell ... See more keywords
Syt-7 overexpression predicts poor prognosis and promotes cell proliferation in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Future oncology"
DOI: 10.2217/fon-2020-0262
Abstract: Aim: To explore the prognostic significance of Syt-7 in hepatocellular carcinoma (HCC) and the potential mechanisms. Methods: Immunohistochemistry was used to examine the expression of Syt-7. Overall survival and disease-free survival were compared between Syt-7… read more here.
Keywords: hepatocellular carcinoma; syt; syt overexpression; proliferation ... See more keywords