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Microenvironmental cooperation promotes early spread and bistability of a Warburg-like phenotype

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-03342-3

Abstract: We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient reservoir (the blood), aimed at characterizing the… read more here.

Keywords: phenotype; warburg like; tissue; microenvironmental cooperation ... See more keywords