Sympathetic nervous system promotes hepatocarcinogenesis by modulating inflammation through activation of alpha1-adrenergic receptors of Kupffer cells
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2016.08.016
Abstract: The sympathetic nervous system (SNS) is known to play a significant role in tumor initiation and metastasis. Hepatocellular carcinoma (HCC) frequently occurs in cirrhotic livers after chronic inflammation, and the SNS is hyperactive in advanced… read more here.
Keywords: sympathetic nervous; nervous system; inflammation; promotes hepatocarcinogenesis ... See more keywords
Histone H1.2 promotes hepatocarcinogenesis by regulating STAT3 signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer science"
DOI: 10.1111/cas.15336
Abstract: Linker histone H1.2 (H1.2), encoded by HIST1H1C (H1C), is a major H1 variant in somatic cells. Among five histone H1 somatic variants, upregulated H1.2 was found in human hepatocellular carcinoma (HCC) samples and in a… read more here.
Keywords: hepatocarcinogenesis regulating; histone; promotes hepatocarcinogenesis; hcc ... See more keywords