Histone lactylation driven by mROS-mediated glycolytic shift promotes hypoxic pulmonary hypertension
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DOI: 10.1093/jmcb/mjac073
Abstract: ABSTRACT Increased mitochondrial reactive oxygen species (mROS) and glycolysis have been established in pulmonary hypertension (PH). However, the effect of elevated mROS on glycolytic shift and how increased glycolysis promotes hypoxic pulmonary artery smooth muscle… read more here.
Keywords: promotes hypoxic; pulmonary hypertension; glycolytic shift; lactylation ... See more keywords