SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity
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DOI: 10.1038/s41418-019-0356-z
Abstract: Lipophagy is a lysosomal lipolytic pathway that complements the actions of cytosolic neutral lipases. Chaperon-mediated autophagy (CMA) triggers lipid droplets (LDs) breakdown, to initiate lipolysis via either cytosolic lipases or macroautophagy. SIRT3, a mitochondrial NAD… read more here.
Keywords: lipophagy chaperon; mediated autophagy; sirt3 promotes; promotes lipophagy ... See more keywords