Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31176
Abstract: Liver fibrosis (LF) is a central pathological process that occurs in most types of chronic liver diseases. Advanced LF causes cirrhosis, hepatocellular carcinoma, and liver failure. However, the exact molecular mechanisms underlying the initiation and… read more here.
Keywords: kinase promotes; liver fibrosis; promotes liver; deletion protein ... See more keywords
Hepatic SIRT6 deficit promotes liver tumorigenesis in the mice models
Sign Up to like & getrecommendations! Published in 2020 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2020.08.007
Abstract: Abstract Background SIRT6 belongs to class III sirtuin family with NAD+ -dependent histone deacetylase activities and controls multiple processes including aging, metabolism and inflammation. In recent years, increasing studies showed tumor suppressor role of SIRT6… read more here.
Keywords: sirt6 deficit; hepatic sirt6; mice models; promotes liver ... See more keywords
MYC-Mediated Translation of PD-L1 Promotes Liver Cancer Immune Escape.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2019-011
Abstract: MYC and KRASG12D exhibit distinct roles in the post-transcriptional regulation of immune checkpoints. read more here.
Keywords: translation promotes; mediated translation; myc mediated; cancer ... See more keywords
[Retracted] PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Oncology reports"
DOI: 10.3892/or.2023.8574
Abstract: Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the tumor images shown in Fig. 4G and H were strikingly similar to tumor images (albeit… read more here.
Keywords: oncology; pea15 promotes; promotes liver; retracted pea15 ... See more keywords