β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
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DOI: 10.1038/s41388-018-0170-y
Abstract: Nuclear activated β-catenin plays a causative role in colorectal cancers (CRC) but remains an elusive therapeutic target. Using human CRC cells harboring different Wnt/β-catenin pathway mutations in APC/KRAS or β-catenin/KRAS genes, and both genetic and… read more here.
Keywords: crc cells; catenin knockdown; catenin; promotes nherf1 ... See more keywords