TPX2 promotes ovarian tumorigenesis by interacting with Lamin A/C and affecting its stability
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5683
Abstract: Ovarian cancer (OC) is one of the fatal gynecologic malignancies. However, there are no effective prognostic or therapeutic indicators for OC. Herein, we aim to reveal the potential function of targeting protein for Xklp2 (TPX2)… read more here.
Keywords: ovarian tumorigenesis; tumorigenesis interacting; promotes ovarian; tpx2 promotes ... See more keywords
Rad50 promotes ovarian cancer progression through NF-κB activation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17017
Abstract: Rad50 is a component of MRN (Mre11-Rad50-Nbs1), which participates in DNA double-strand break repair and DNA-damage checkpoint activation. Here, we sought to investigate the clinical and functional significance of Rad50 in high-grade serous ovarian cancer… read more here.
Keywords: ovarian cancer; activation; rad50 promotes; rad50 ... See more keywords